NewsIbuprofen: Unexpected ally in diabetes treatment

Ibuprofen: Unexpected ally in diabetes treatment

A common painkiller and anti-inflammatory drug, available over-the-counter and present on the market for many years, can still surprise us. Scientists have discovered an unexpected side effect of ibuprofen. However, it turns out that it may be beneficial.

Scientists have discovered a new, unusual effect of a popular painkiller and anti-inflammatory drug.
Scientists have discovered a new, unusual effect of a popular painkiller and anti-inflammatory drug.
Images source: © Wikimedia Commons
Barbara Kwiatkowska

What do you need to know?

  • What did the scientists discover? Researchers from Rutgers University demonstrated that ibuprofen can inhibit receptors responsible for tasting sweetness. This may affect sugar intake and metabolism.
  • What are the potential applications? The discovery could be significant in the treatment of diabetes. However, experts warn against using ibuprofen as an immediate remedy for this purpose.
  • What are the risks? Regular use of ibuprofen is associated with the risk of side effects such as stomach ulcers, kidney damage, and cardiovascular problems.

How does ibuprofen affect taste perception?

Scientists from Rutgers University made a groundbreaking discovery regarding ibuprofen, a popular painkiller. Studies have shown that this drug can reduce the perception of sweetness by inhibiting TAS1R2-TAS1R3 receptors. These receptors are found not only on the tongue but also in other organs such as the stomach and pancreas. "What we discovered is that ibuprofen and naproxen inhibit activation of the sweet taste receptor in people, as well as in human cells," explained Prof. Paul Breslin in MedicalXpress.

Can ibuprofen help in treating diabetes?

In laboratory tests, participants reported a decrease in the perception of sweetness after rinsing their mouths with an ibuprofen solution. This suggests that the drug may play a role in managing sugar metabolism. However, experts warn against using ibuprofen as an immediate remedy for treating diabetes due to potential side effects. Specialists caution that potential side effects can include stomach ulcers, kidney problems, and cardiovascular complications.

What are other benefits and risks associated with ibuprofen?

Previous studies have linked regular use of ibuprofen with a reduced risk of metabolic diseases, such as diabetes, Alzheimer's disease, and colorectal cancer. Nevertheless, long-term use of this drug is associated with the risk of serious side effects, especially at high doses.

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